Hyposensitization agent

Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Plant proteins – e.g. – derived from legumes – algae or...

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

530370, 530406, 530410, 530411, 530359, 424 91, A61K 3936

Patent

active

050736280

ABSTRACT:
A novel hyposensitization agent was prepared by covalently attaching a saccharide to a cedar pollen allergen having a partial amino acid sequence of Ala-Ile-Asn-Ile-Phe-Asn- beginning at its N-terminal. The hyposensitization agent, when compared with an intact cedar pollen allergen, extremely accelerates the production of immunoglobulin G and M antibodies which are specific to intact cedar pollen allergen, but extremely reduces the production of immunoglobulin E antibody which is specific to the allergen. Thus, the hyposensitization agent is administrable to cedar pollinosis patients with no anaphylaxis and allergy, and cuts hyposensitization period to about 1/3 to 1/200.

REFERENCES:
patent: 4939239 (1990-07-01), Matsuhashi et al.
Chem. Abstracts, vol. 112, 1990, 62606s, effective date Mar. 22, 1989, Hayashibara.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Hyposensitization agent does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Hyposensitization agent, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Hyposensitization agent will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-836301

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.