Hypolipidemic agents RO- or RS- substituted furoic acids, esters

Details Hypolipidemic agents RO- or RS- substituted furoic acids, esters Hypolipidemic agents RO- or RS- substituted furoic acids, esters

1973-04-02

1978-08-29

Raymond, Richard L.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

26029367, 26032636, 2603473, 2603475, 42424852, 42424853, 42424855, 424250, 424267, 424274, 424285, 544152, 544379, C07D30768

Patent

active

041103513

ABSTRACT:
Substituted furoic acids and esters and pharmaceutically acceptable salts thereof of the following general structure are useful as hypolipidemic agents: ##STR1## wherein Y represents oxygen or divalent sulfur; R represents a straight or branched alkyl chain containing from 10 to 20 carbon atoms and may be saturated or may be unsaturated containing from 1 to 4 double bonds; R.sup.1 represents hydrogen, straight or branched lower alkyl of from 1 to 6 carbon atoms, benzyl, phenethyl, pyridylmethyl, alkane-poly-yl containing from 3 to 6 carbon atoms, 1,2,3,4,5,6-cyclohexanehexayl, or Z; Z represents

REFERENCES:
burger, Medicinal Chemistry, part II, pp. 1123-1165 (third edition), (1970).
Manly, D. G. et al., "Jour. of Organic Chem.", vol. 21, pp. 516-519.

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