Hypoglycemic 5-substituted oxazolidine 2,4-diones

Details Hypoglycemic 5-substituted oxazolidine 2,4-diones Hypoglycemic 5-substituted oxazolidine 2,4-diones

1985-10-03

1987-08-25

Daus, Donald G.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514372, 548180, 548204, 548214, 548221, 548227, 549398, 549462, C07D26344, A61K 3142

Patent

active

046893369

ABSTRACT:
Hypoglycemic 5-chromanyl, 2,3-dihydro-5-benzo[b]-furanyl, 5-pyridyl, 5-quinolyl, 5-pyrrolyl, 5-indolyl, 5-thiazolyl, 5-oxazolyl, 5-isothiazolyl and 5-isoxazolyl oxazolidine-2,4-diones and the pharmaceutically-acceptable salts thereof; certain 3-acylated derivatives thereof; a method of treating hyperglycemic animals therewith; and intermediates useful in the preparation of said compounds.

REFERENCES:
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Ciamacian and Silber, Ber. 19, pp. 1708-1714 (1886).
Clark-Lewis, Chem. Rev. 58, pp. 63-99 (1958).
Brink and Freeman, J. Neuro. Chem. 19 (7), pp. 1783-1788 (1972).

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