Hypoglycaemic peptides

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai

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Details

514 16, 514 17, 514 18, 514 19, 530328, 530329, 530330, 530331, 548485, 548544, 548545, A61K 3804, C07K 500, C07K 700

Patent

active

060488409

ABSTRACT:
This invention relates to novel insulin-potentiating hypoglycaemic compounds.

REFERENCES:
patent: 4496521 (1985-01-01), Lewis
Thompson, et al, Drug, Design and Discovery, vol. 13, pp. 52-72, 1995 (Exhibit C).
Chemical Abstract, vol. 112, 1990.
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CAPLUS on STN database; No. 1981:587631. Fujino et al. "The 4=methoxy-2, 6-dimethylbenzenesulfonyl (Mds): a new protecting group of guanidino functin in peptdie synthesis" 1980.
Murray et al., "Metabolism of a Synthetic L-Isoaspartal-Containing Hexapeptide in Erythrocyte Extracts", Journal of Biological Chemistry, vol. 261, No. 1, pp. 308-312, Jan. 5, 1986.
Kimura et al., "Strategy for Sythesis of Large Peptides: An Application to the Total Sythesis of Human Parathyroid Hormone [hPTH (1-84)]", Biopolymers, vol. 20, No. 9, pp. 1823-1832 (abstract only), 1981.
Ondetti et al., Biochemistry 1968, 7 4069-4075.
Pullin et al., Int. J. Peptide Protein Res., 1981 18 318-323.
Perseo et al., Int. J. Peptide Protein Res., 1986 27 51-60.
Chemical Abstracts, 1985 102 No. 167166v.
Chemical Abstracts, 1980 92 No. 198744m.
Partial European Search Report.

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