Hypocholesterolemically and/or hypotriglyceridemically active pr

Details Hypocholesterolemically and/or hypotriglyceridemically active pr Hypocholesterolemically and/or hypotriglyceridemically active pr

1986-01-14

1989-01-10

Weimar, Elizabeth C.

Drug, bio-affecting and body treating compositions

Whole live micro-organism, cell, or virus containing

Genetically modified micro-organism, cell, or virus

435885, 514824, A61K 3574, C12N 120, C12R 146

Patent

active

047972785

ABSTRACT:
A bacterial cell product orally administered to lower serum cholesterol and/or triglyceride level in mammals obtained by cultivating a microorganism belonging to the genus Streptococcus and having a N-acetyl-.beta.-D-glucosaminidase activity in an adequate culture medium therefor, and collecting the cultivated microorganism from the resultant culture.

REFERENCES:
patent: 3567821 (1971-03-01), Nouvel
patent: 4190649 (1980-02-01), Beljanski
patent: 4259442 (1981-03-01), Gayral
patent: 4335239 (1982-06-01), Beljanski
patent: 4389396 (1983-06-01), Hinterland et al.
patent: 4448768 (1984-05-01), Coleman et al.
patent: 4536496 (1985-08-01), Shimizu et al.
patent: 4687764 (1987-08-01), Kawai et al.
Nord et al., "Formation of Glycoside-Hydrolases by Oral Streptococci"; Archs. Oral Biol., vol. 18, pp. 391-402; 1973.
Watanabe et al.; "Studies on Streptococci"; Microbiol. Immun., vol. 25, No. 3, pp. 257-269; 1981.
Kawai et al., "Studies on Streptococci"; Microbiol. Immun., vol. 26, No. 5, pp. 363-373; 1982.
Kawai et al.; "Distribution & Colonization of Human Fecal Streptococci"; Am. J. Clin. Nutr., Nov. 1980; vol. 33, pp. 2458-2461.
Hussain et al.; "Activation of Lipolytic Activity of Streptococcus Faecalis by Nitrosoguanidine"; Folia Microbiol.; vol. 21, pp. 73, 74, (1976).
Medical Tribune, vol. 25, No. 22, (Aug. 1, 1984), pp. 1 and 2.
Kawai et al.; "Intestinal Enzyme Activity in Germ-Free Conventional & Gnotobiotic Rats Associated with Indigenous Microorganisms"; Infection & Immunity, vol. 19, No. 3, pp. 771-778.
Kawai et al.; "Quantitative and Qualitative Alteration of Mucasal Alkaline Phosphatase by Intestinal Microbes in the Upper Digestive Tract of the Rat"; Am. J. of Clin. Nutr., vol. 32, Jan. 1979, pp. 187-188.
Kawai et al.; "Intestinal Microflora and Aging: Age-Related Change of Lipid Metabolism in Germ-Free and Conventional Rats"; Mech. of Aging & Dev., vol. 16, (1981); pp. 149-158.
Yazawa et al.; "Intestinal Microflora and Aging: Age-Related Change of Enzymes in the Liver and the Small Intestine of Germ-Free and Conventional Rats"; Mech. of Aging & Dev.; vol. 17, (1981), pp. 173-182.
Moore et al.; "Cell-Free Protein Synthesis: Effects of Age and State of Ribosomal Aggregation"; Science, vol. 154, Dec. 9, 1966, pp. 1350-1353.
Herson et al.; "Protein Synthesis in Cell-Free Extracts of Streptococcus Faecalis"; J. Bacteriology, Dec. 1969; pp. 1350-1354.
Rao et al.; "Influence of Milk and Thermophilus Milk on Plasma Cholesterol Levels and Hepatic Cholesterolgenesis in Rats"; J. Food Sci., vol. 46, (1981), pp. 1339-1341.
Salvioli et al.; "Bile Acid Transformation by the Intestinal Flora and Cholesterol Saturation in Bile"; Digestion, vol. 23, pp. 80-88; (1982).
Rall, et al., "Human Apolipoprotein E," J. Biol. Chem., vol. 257(8), pp. 4171-4178, (1982).
Slobodskaya, "Comparison of Hypocholesterolemic Effect . . . , " Biol. Abstract, 76(10), (1983).
Bergy's Manual of Determinative Bacteriology, 8th Ed., Williams and Williams, 1974.

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