Hyperthermia agent for malignant tumor comprising cytokine...

Details Hyperthermia agent for malignant tumor comprising cytokine... Hyperthermia agent for malignant tumor comprising cytokine...

2007-10-16

2007-10-16

Foley, Shanon (Department: 1642)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

C424S646000

Reexamination Certificate

active

10815273

ABSTRACT:
The present invention discloses a hyperthermia agent for malignant tumor which comprises cytokine or a vector in which a cytokine gene is integrated so that cytokine can express in malignant tumor cells, and magnetic fine particles, and a hyperthermia method using the same.

REFERENCES:
Yanase et al (Jpn J Cancer Research, 1998, 89:463-470).
O'Day et al (Clinical Cancer Research, 2002, 8:2775-2781).
Ito et al (Cancer Gene Therapy, 2001, 8:649-654).
Shinkai et al I (Biotechnol Appl Biochem, 1994, 21:125-137, IDS).
Shinkai et al II (Jpn J Hyperthermic Oncol, 1994, 10:177, IDS, abstract only).
Ito et al (J of Bioscience and Bioengineering, 2005, 100:1-11).
Shinkai, et al., “Antibody-conjugated magnetoliposomes for targeting cancer cells and their application in hyperthermia”, Biotechnol. Appl. Biochem. 21, pp. 125-137, 1994.
Shinkai, et al., “Heat properties of magnetoliposomes for local hyperthermia”, Jpn. J. Hyperthermic Oncol. 10(2), pp. 168-177, 1994. (Abstract translation only).

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