Hypersensitive constriction velocity method for diagnosing Alzhe

Details Hypersensitive constriction velocity method for diagnosing Alzhe Hypersensitive constriction velocity method for diagnosing Alzhe

1995-05-23

1997-04-08

Hindenburg, Max

Surgery

Truss

Pad

A61B 1300

Patent

active

056178727

ABSTRACT:
The present invention provides a non-invasive method for diagnosing Alzheimer's disease in a living human subject. The diagnostic method employs a non-invasive automated apparatus which can repetitively measure pupil constriction velocity for a pre-chosen duration both before and after stimulation by visible light; and cumulatively record such measured pupil constriction velocity data as is obtained over time. The method also administers at least one neural transmitter mediator to a targeted eye of the living subject in an amount insufficient to cause marked changes in pupillary dynamic response in a person who is not afflicted with Alzheimer's disease. The marked hypersensitivity of an Alzheimer's dementia patient to the administered neural transmitter mediator causes a marked change in pupil constriction velocity and thus serves as the means diagnostically to determine and identify an individual living human subject as being afflicted with Alzheimer's disease.

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