Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Carbohydrate doai
Reexamination Certificate
2008-07-01
2008-07-01
Lankford, L Blaine (Department: 1651)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Carbohydrate doai
C514S054000, C536S002000
Reexamination Certificate
active
07393841
ABSTRACT:
The invention relates to the use of hyperbranched amylopectin which has an average branch degree of between >10 and 25 mol % and a molecular weight (Mw) ranging from 40.000-800.000 Dalton and the derivatives thereof in methods for surgical or therapeutic treatment of human or animal bodies or in a diagnostic method, preferably as a plasma volume expander. Plasma volume expanders based on hydroxy-ethylated amylopectin have, as a result of hydroxy ethylation, hitherto exhibited the disadvantage of incomplete metabolism and thus temporary tissue storage which is linked to side-effects. According to the invention, novel plasma expanders based on polysaccharides which do not exhibit the same disadvantages as the former are provided. Improved, completely metabolised plasma expanders based on hyperbranched amylopectin which can be obtained therefrom so that native plant-amylopectins are altered-by transglycosylation in such a way the adjustable, high degree of branching enables control of the serum-α-amylase decomposition so that no or only a very insignificant degree of hydroxy ethylation is necessary.
REFERENCES:
patent: 4111199 (1978-09-01), Djerassi
patent: 4125492 (1978-11-01), Cuatrecasas et al.
patent: 4454161 (1984-06-01), Okada et al.
patent: 4629698 (1986-12-01), Nitsch et al.
patent: 3029307 (1982-03-01), None
patent: 19628705 (1998-01-01), None
patent: 10112825 (2002-10-01), None
patent: 0418523 (1991-03-01), None
patent: 0418523 (1991-03-01), None
patent: 418945 (1991-03-01), None
patent: 1 075 839 (2001-02-01), None
patent: 1 279 356 (1972-06-01), None
patent: WO 00 18893 (2000-04-01), None
The Merck Index, 12th edition. Budavari, S. et al., Eds. Merck & Co.: Whitehouse Station, NJ. 1996. Entry 4506 (Glycogen), pp. 765-766.
Database Chemabs ′Online!, Chemical Abstracts Service, Columbus, Ohio, US;, “Manufacture of Highly-Branched Starch inhibition of Retrogradation of Starch, and Food Containing the Starch,” retrieved from STN, Accession No. 135:317549, XP 002222974, Zusammenfassung & JP 2001 294601 A, Oct. 23, 2001.
Gunja ,Zeenat H., et al., “Enzymic Conversion of Amylopectin into a Glycogen-type Polysaccharide,” Chemistry & Industry., p. 1017 (1959).
Fernandez Susan E.
Hamilton, Brook, Smith & Reyonlds, P.C.
Lankford L Blaine
Supramol Parenteral Colloids GmbH
LandOfFree
Hyperbranched amylopectin for use in methods for surgical or... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Hyperbranched amylopectin for use in methods for surgical or..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Hyperbranched amylopectin for use in methods for surgical or... will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-2769076