Hygromycin A derivatives

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Reexamination Certificate

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Details

C514S023000, C514S025000, C514S218000, C514S233800, C514S253110, C514S254110, C514S316000, C514S321000, C514S338000, C514S397000, C514S414000, C514S422000, C536S016800, C536S017900, C536S018100, C540S575000, C544S148000, C544S364000, C544S377000, C546S187000, C546S197000, C546S283700, C548S311700, C548S454000, C548S526000, C549S435000

Reexamination Certificate

active

06867230

ABSTRACT:
This invention relates to compounds of the formulaand to pharmaceutically acceptable salts, prodrugs and solvates thereof, wherein R1, R2, R3and R10are as defined herein. The compounds of formula 1 are antibacterial and antiprotozoal agents that may be used to treat various bacterial and protozoal infections and disorders related to such infections. The invention also relates to pharmaceutical compositions containing the compounds of formula 1, methods of treating bacterial and protozoal infections by administering the compounds of formula 1.

REFERENCES:
patent: 6245745 (2001-06-01), Hayward et al.
patent: WO 9957125 (1999-11-01), None
patent: WO 9957127 (1999-11-01), None
patent: WO 0032616 (2000-06-01), None
patent: WO 0032616 (2000-08-01), None
patent: WO 0130795 (2001-05-01), None
B. H. Jaynes et al., Bioorganic & Medicinal Chemistry Letters, vol. 3, No. 8, pp. 1531-1536, 1993.

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