Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – 9,10-seco- cyclopentanohydrophenanthrene ring system doai
Patent
1984-01-30
1985-03-19
Roberts, Elbert L.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
9,10-seco- cyclopentanohydrophenanthrene ring system doai
2603972, C07J 900
Patent
active
045059063
ABSTRACT:
The invention provides, as novel vitamin D derivatives, isomers of 25-hydroxyvitamin D.sub.2 and 1.alpha.,25-dihydroxyvitamin D.sub.2 characterized by a double bond at the 23,24-position.
The compounds are characterized by vitamin D-like activity as assessed by competitive binding assays and would therefore, find application as substitutes for vitamin D or various of its metabolites in their various known applications and in the treatment of vitamin D-responsive bone diseases.
REFERENCES:
patent: 4360471 (1982-11-01), DeLuca et al.
DeLuca Hector F.
Schnoes Heinrich K.
Sicinski Rafal R.
Tanaka Yoko
Bremer Howard W.
Roberts Elbert L.
Wisconsin Alumni Research Foundation
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