Hydroxyquinazolines and their use as intermediates for pharmaceu

Chemistry of carbon compounds – Miscellaneous organic carbon compounds – C-metal

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260562P, 260562B, 260566A, 260566R, 260553C, 260544Y, 424244, 544286, 562605, 562604, C07D24334, C07D24328, C07D23980

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active

041418956

ABSTRACT:
6-Substituted-2-halofluoromethyl-1,2-dihydro-2-hydroxy-1-methyl-4-phenylqui nazolines and their use as intermediates in the preparation of 3-fluorobenzodiazepines, which are useful as tranquilizers, muscle relaxants and sedatives.

REFERENCES:
patent: 3440281 (1969-04-01), Fryer et al.
Yamada et al., "Bull. Chem. Soc.," (Japan), vol. 47, pp. 343-347, (1974).
Bell et al., "J. Organic Chem.," vol. 27, pp. 562-566, (1962).

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