Organic compounds -- part of the class 532-570 series – Organic compounds – Rare earth containing
Reexamination Certificate
2005-01-25
2005-01-25
Jones, Dameron L. (Department: 1616)
Organic compounds -- part of the class 532-570 series
Organic compounds
Rare earth containing
C424S001110, C424S001650, C544S001000, C544S224000, C544S180000, C549S200000
Reexamination Certificate
active
06846915
ABSTRACT:
The present invention provides hydroxypyridinone and hydroxypyrimidone chelating agents. Also provides are Gd(III) complexes of these agents, which are useful as contrast enhancing agents for magnetic resonance imaging. The invention also provides methods of preparing the compounds of the invention, as well as methods of using the compounds in magnetic resonance imaging applications.
REFERENCES:
Cohen et al, Inorg. Chem., Nov. 17, 2000, vol. 39, pp. 5747-5756.*
Alessandra Villa, et al., “Force Field Parametrization for Gadolinium Complexes Based on ab Initio Potential Energy Surface Calculations,”J. Phys. Chem. A,104:3421-3429 (2000).
Doble Daniel M. J.
Raymond Kenneth N.
Sunderland Christopher J.
Thompson Marlon
Jones Dameron L.
Morgan & Lewis & Bockius, LLP
The Regents of the University of California
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