Hydroxymethyl benzodiazepine derivatives

Details Hydroxymethyl benzodiazepine derivatives Hydroxymethyl benzodiazepine derivatives

1974-07-11

1977-02-01

Rollins, Alton D.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

2602948C, 2602949, 260295F, 260296B, 424244, 424263, C07D24320, C07D40104

Patent

active

040061353

ABSTRACT:
Novel 1-hydroxymethyl-2-(N-alkyl-N-hydroxymethyl)amino-1H-1,4-benzodiazepines and their 4-oxides, and acid addition salts thereof. Also a process for their preparation from 2-alkyl-amino-3H-1,4-benzodiazepines and their 4-oxides.

REFERENCES:
patent: 3391138 (1968-07-01), Archer et al.
patent: 3682888 (1972-08-01), Podesva et al.
patent: 3819602 (1972-06-01), Fryer et al.
Greenblatt et al., Benzodiazepines in Clinical Practice, (Raven Press, N.Y., 1974) pp. 10-12.

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