Hydroxylation of methyl groups in aromatic heterocycles by micro

Details Hydroxylation of methyl groups in aromatic heterocycles by micro Hydroxylation of methyl groups in aromatic heterocycles by micro

1991-09-23

1993-06-08

Schwartz, Richard A.

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Preparing heterocyclic carbon compound having only o, n, s,...

435156, 435122, 435120, 435121, 435126, C12P 722, C12P 1700, C12P 1712, C12P 1714

Patent

active

052178846

ABSTRACT:
A process using microorganisms which contain genes, which form an active xylene monooxygenase, which form no effective, chromosomally or plasmid-coded alcohol hydrogenase, and which are, thus, capable of hydroxylating methyl groups on aromatic 5- or 6-atom heterocycles to the corresponding hydroxymethyl derivatives, for the production of hydroxymethylated 5- or 6-atom heterocycles.

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