Hydroxylapatite base porous beads filler for organism and method

Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Implant or insert

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424423, 424405, 424489, 424502, 264 44, 264102, 264129, 264273, 264279, 2642979, 523115, 523116, 623 16, A61K 916, A01N 102, A61F 228, B05D 722

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057283958

ABSTRACT:
A hydroxylapatite base porous beads filler for use in cure of an injured or diseased part of bone of an organism. The porous filler is comprised of fired hydroxylapatite base beads each of which is formed with many pores. Each pore of the bead has a diameter of 1 to 100 .mu.m and a length larger than the diameter. Each bead has a porosity of 10 to 50% and a diameter of 0.02 to 20 mm. The pores of the bead may be filled with a solution containing a pharmaceutical in order to promote the cure of the injured or diseased part.

REFERENCES:
patent: 4373217 (1983-02-01), Draenert
patent: 4548959 (1985-10-01), Nagai
patent: 4610692 (1986-09-01), Eitenmuller
patent: 4677140 (1987-06-01), Shiotsu
patent: 4684673 (1987-08-01), Adachi
patent: 4698375 (1987-10-01), Dorman
patent: 4988362 (1991-01-01), Toriyama
patent: 5034059 (1991-07-01), Constantz
Basic Studies of Hydroxyapatite, Masami Hori, Biometerial, vol. 8, No. 1, pp. 11-22 (1990).

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