Hydroxylamines with hypoglycemic activity

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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548958, A61K 31635, C07D49156

Patent

active

055456596

ABSTRACT:
Novel 1-(2-,3- or 4-hydroxylaminobenzensulfonyl-1a,2,6,6 a-tetrahydro-1H,4H-[1,3]-dioxepino[5,6-b]azirines with hypoglycemic activity are prepared by selective reduction of appropriate 1-(2-,3- or 4-nitrobenzenesulfonyl) derivatives.

REFERENCES:
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patent: 3715397 (1973-02-01), Rylander et al.
patent: 3927101 (1975-12-01), Le Leduc
patent: 4723030 (1988-02-01), Davis
patent: 5166435 (1992-11-01), Sharma et al.
patent: 5266173 (1993-11-01), Bandlish et al.
patent: 5286744 (1994-02-01), Dumic et al.
Dumic et al, "1-Sulfonyl-1a,2,6,6a-tetrahydro, etc" Tet. Let. 34 (22) pp. 3639-3642 (1993).

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