Hydroxyindoles, their use as inhibitors of phosphodiesterase...

Details Hydroxyindoles, their use as inhibitors of phosphodiesterase... Hydroxyindoles, their use as inhibitors of phosphodiesterase...

2007-01-09

2007-01-09

Morris, Patricia L. (Department: 1625)

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

Reexamination Certificate

active

10081642

ABSTRACT:
The invention relates to new hydroxyindoles of the Formula,their use as inhibitors of phosphodiesterase 4 and processes for their preparation.

REFERENCES:
patent: 2814625 (1957-11-01), Speeter
patent: 2825734 (1958-03-01), Speeter
patent: 2870162 (1959-01-01), Speeter et al.
patent: 2930797 (1960-03-01), Anthony et al.
patent: 3028393 (1962-04-01), Szmuszkovicz
patent: 3188313 (1965-06-01), Archer
patent: 3196162 (1965-07-01), Sarett et al.
patent: 3259622 (1966-07-01), Shen et al.
patent: 3271416 (1966-09-01), Shen
patent: 3342834 (1967-09-01), Shen
patent: 3459770 (1969-08-01), Freed et al.
patent: 3527761 (1970-09-01), Archibald et al.
patent: 3578669 (1971-05-01), Zenith
patent: 3642803 (1972-02-01), Welstead, Jr.
patent: 5192770 (1993-03-01), Clark et al.
patent: 5411972 (1995-05-01), Komoto et al.
patent: 5464861 (1995-11-01), Dobrusin et al.
patent: 6008231 (1999-12-01), Lebaut et al.
patent: 2057181 (1992-06-01), None
patent: 2195850 (1996-02-01), None
patent: 2215013 (1998-03-01), None
patent: 0 490 263 (1992-06-01), None
patent: 97/23457 (1997-07-01), None
patent: WO 97/23457 (1997-07-01), None
patent: 98/09946 (1998-03-01), None
patent: 01/47916 (2001-07-01), None
CA 129:4586, Albaugh et al., 1998.
CA 109: 122607, Hayahi et al., 1988.
CA 98: 100717, 1983.
CA 94: 65469, Hurnaus et al. 1981.
Matsuoka et al, “Hydroxyindole” CA 101:23333 (1984).
Rehse et al, “Affinity to 5-HT receptors”, CA 108:75173.
Allen et al, “Reflectance Spectrum and, etc” CA 66:33303 (1967).
Itoh et al, “Synthesis, Physiochemical, etc” J. Org. Chem. 1997, 62, 5898-5907.
Liu et al, “Regiospecific Bromination, etc” J. Org Chem. 1997, 62, 7447-7456.
Von Angerer et al, I, “2-Phenylindoles, etc”, J. Med. Chem., 1984, 27, 1439-1447.
Von Angerer et al II, “2-(Hydroxyphenyl)indoles, etc” J. Med. Chem, 1983, 26, 113-116.
Abstract—Synthesis and Pharmacological activity of . . . in nature, Bertaccini, et al. (1967), 22(4), 229-44.
Indole Inhibitors of Human . . . acetamides, Dillard, et al. J. Med. Chem, 1996, pp. 5119-5136.

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