Organic compounds -- part of the class 532-570 series – Organic compounds – Amino nitrogen containing
Patent
1997-12-29
1999-04-06
Burn, Brian M.
Organic compounds -- part of the class 532-570 series
Organic compounds
Amino nitrogen containing
C07C21103
Patent
active
058921133
ABSTRACT:
This invention relates to a class of aminimides structurally characterized as an acyl nitrogen-nitrogen ylide such that the acyl moiety possess the structural diversity element G, the quaternary nitrogen possess structural diversity elements E and F, and the quaternary nitrogen is bonded to a hydroxyethyl substituent, which in turn is bonded to an aminomethylene moiety that possess structural diversity elements A and B from the amino group and diversity element c from the methylene substituent, as shown below, ##STR1## wherein structural diversity element A, B, C, D, E, F and G are chosen from the set of elements consisting of substituted and unsubstituted as well as branched and straight chain alkyl, aryl, alkaryl, aralkyl, carbocyclic, heterocyclic, hydrogen, amino acid, peptide, polypeptide, protein, depsipeptide, carbohydrate derivatives, nucleotide derivatives, oligonucleotide derivatives, naturally occurring or synthetic organic structural motifs, reporter elements, organic moieties containing at least one polymerizable group, macromolecular component, resin, silicate, other surface and particle support, the diversity elements can be the same, can be different, and can also be connected to form a ringed to several ringed species.
REFERENCES:
patent: 3410880 (1968-11-01), Brockenhurst
patent: 3450673 (1969-06-01), McKillip
patent: 3485806 (1969-12-01), Bloomquist et al.
patent: 3488327 (1970-01-01), Kollinsky et al.
patent: 3488389 (1970-01-01), McKillip
patent: 3499032 (1970-03-01), Clemens et al.
patent: 3511894 (1970-05-01), Markert
patent: 3527802 (1970-09-01), Slagel
patent: 3555095 (1971-01-01), Slagel
patent: 3565868 (1971-02-01), Sedor et al.
patent: 3567725 (1971-03-01), Grabowski et al.
patent: 3583950 (1971-06-01), Kollinsky et al.
patent: 3598790 (1971-08-01), Kollinsky et al.
patent: 3641145 (1972-02-01), Culbertson
patent: 3664990 (1972-05-01), Slagel
patent: 3671473 (1972-06-01), Sedor et al.
patent: 3676453 (1972-07-01), Pines et al.
patent: 3704128 (1972-11-01), Koda et al.
patent: 3706797 (1972-12-01), McKillip et al.
patent: 3706800 (1972-12-01), Hartlage et al.
patent: 3715343 (1973-02-01), Slagel et al.
patent: 3728387 (1973-04-01), Freis et al.
patent: 3756994 (1973-09-01), Culbertson
patent: 3781319 (1973-12-01), Wawzonek et al.
patent: 3794495 (1974-02-01), Ishihara et al.
patent: 3803220 (1974-04-01), Gasman
patent: 3811887 (1974-05-01), Ishihara et al.
patent: 3818065 (1974-06-01), Schoellkopf et al.
patent: 3828007 (1974-08-01), Throckmorton
patent: 3850969 (1974-11-01), Grimm et al.
patent: 3893974 (1975-07-01), Niino et al.
patent: 3898087 (1975-08-01), Brutchen et al.
patent: 3904749 (1975-09-01), McKillip
patent: 3925284 (1975-12-01), Carleton et al.
patent: 3934029 (1976-01-01), Kabara
patent: 3934031 (1976-01-01), Kabara
patent: 3934035 (1976-01-01), Kabara
patent: 3946131 (1976-03-01), Biefeld et al.
patent: 3948866 (1976-04-01), Pennewiss et al.
patent: 3963703 (1976-06-01), Culbertson
patent: 3963776 (1976-06-01), Middleton
patent: 3968065 (1976-07-01), Morris et al.
patent: 3969298 (1976-07-01), Gasman
patent: 3983166 (1976-09-01), Samour
patent: 3985807 (1976-10-01), Grimm et al.
patent: 4005055 (1977-01-01), Miron et al.
patent: 4016340 (1977-04-01), Kolesinski et al.
patent: 4022623 (1977-05-01), Fitzgerald et al.
patent: 4046658 (1977-09-01), Brown
patent: 4067830 (1978-01-01), Kresta
patent: 4070348 (1978-01-01), Kriemer et al.
patent: 4078901 (1978-03-01), Sung et al.
patent: 4080206 (1978-03-01), Kolesinski et al.
patent: 4097444 (1978-06-01), Teige et al.
patent: 4102916 (1978-07-01), Falk
patent: 4122159 (1978-10-01), Madrange et al.
patent: 4140680 (1979-02-01), Sullivan
patent: 4162355 (1979-07-01), Tsibris
patent: 4189481 (1980-02-01), Kabara
patent: 4212905 (1980-07-01), Talbris
patent: 4213860 (1980-07-01), Tsibris
patent: 4217364 (1980-08-01), Kabara
patent: 4260705 (1981-04-01), Tsibris
patent: 4280008 (1981-07-01), Scheollkopf et al.
patent: 4304705 (1981-12-01), Heilmann et al.
patent: 4378411 (1983-03-01), Heilmann et al.
patent: 4424272 (1984-01-01), Taylor
patent: 4451619 (1984-05-01), Heilmann et al.
patent: 4485236 (1984-11-01), Rasmussen et al.
patent: 4548981 (1985-10-01), Kolesinski et al.
patent: 4563467 (1986-01-01), Soler
patent: 4617253 (1986-10-01), Taylor et al.
patent: 4624995 (1986-11-01), Katritzky et al.
patent: 4645711 (1987-02-01), Winslow
patent: 4667012 (1987-05-01), Rasmussen et al.
patent: 4670528 (1987-06-01), Taylor et al.
patent: 4695608 (1987-09-01), Engler et al.
patent: 4705824 (1987-11-01), Lin
patent: 4737560 (1988-04-01), Heilmann et al.
patent: 4740568 (1988-04-01), Katritzky et al.
patent: 4777217 (1988-10-01), Rasmussen et al.
patent: 4777276 (1988-10-01), Rasmussen et al.
patent: 4785070 (1988-11-01), Rasmussen et al.
patent: 4816554 (1989-03-01), Katritzksy et al.
patent: 4841021 (1989-06-01), Katritzky et al.
patent: 4852969 (1989-08-01), Babirad et al.
patent: 4871824 (1989-10-01), Heilmann et al.
patent: 4874822 (1989-10-01), Rasmussen et al.
patent: 4898923 (1990-02-01), Katritzky et al.
patent: 4948715 (1990-08-01), Hulme-Lowe et al.
patent: 4981933 (1991-01-01), Fazio et al.
patent: 5013795 (1991-05-01), Coleman et al.
patent: 5039813 (1991-08-01), Fazio et al.
patent: 5066559 (1991-11-01), Elmasry et al.
patent: 5075352 (1991-12-01), Elmasry
patent: 5081197 (1992-01-01), Heilmann et al.
patent: 5091489 (1992-02-01), Heilmann et al.
patent: 5094766 (1992-03-01), Kepuscinski et al.
patent: 5138071 (1992-08-01), Schoellkopf et al.
patent: 5147957 (1992-09-01), Kumar
patent: 5149806 (1992-09-01), Moren et al.
patent: 5157108 (1992-10-01), Krepski et al.
patent: 5157145 (1992-10-01), Schoellkopf et al.
patent: 5175081 (1992-12-01), Krepski et al.
patent: 5185102 (1993-02-01), Harelstad et al.
patent: 5194623 (1993-03-01), Krepski et al.
patent: 5200471 (1993-04-01), Coleman et al.
Tetrahedron Letters, 27, 6319 (1986).
Kardiologisisa, "Bioelectrical Mechanism", vol. 31, No. 7, 1991, pp. 52-55.
Kardiologisisa, vol. 30, No. 8, 1990, pp. 69-72.
J. Hetegel Chem., 1972, 9, 687-690, "Aminimides IX(1). A general Synthesis of 1-Substituted-2-imidazolidinones(2)", by David Aelony et al.
J. Org. Chem., vol. 41, No. 4, 1976, 715-716, "Acyl Migration in 2-Hydroxylalkyl Aminimides", by Meir Asscher.
Biopolymers, vol. 17, 1693-1711 (1978), "Experimental Conformational Study of Two Peptides Containing a-Aminoisobutyric Acid. Crystal Structure of N-Acetyl-a-Aminoisobutyric Acid Methylamide" by A. Aubry et al.
Tetrahedron Letters No. 31, pp. 2691-2694, 1976, "Pyridines as Leaving Groups in Synthetic Transformations: Nucleophilic Displacements of Amino Groups, and Novel Preparations of Nitriles and Isocyanates", by J.B. Bapat et al.
University College, Hull, Sep. 27, 1952, pp. 453-456, "The Dehydration and Racemisation on N-Acyl-L-aspartic Acids by Acetic Anhydride", by C.C. Barker.
Acta Chem. Scand. B 33 (1979) No. 2, "Electron Deficient Heteroar matic Ammonioamidates. XVII. N-(3-Quinazolinio)amindates. VI. The Photochemistry of N-(30Quinazolinio)amidates in the Presence of .alpha.-Toluenethiol", by G. Barta-Szalai et al.
J. Chem. Socl. Perkin Trans. I 1983, "Electron Deficient Heteroaromatic Ammonioamides. Part 24..sup.1. N-(Quinazolin-3-io)amindates. Part 11..sup.2 The Photochemistry of N-(6,7-Methylenedioxyquinazolin-3-io)amidates in Acetone", by Gizella Barta-Szalai et al.
J. Heterocyclic Chem., 23, 375, 1986, "Novel Synthesis of ", by S. Batori.
J. Heterocyclic Chem., 25, 437 (1988), "Regioselectivity in Methylation and
J. Heterocyclic Chem., 27, 1673 (1990), "Synthesis and Regiospecificity in
J.C.S. Perkin II, 1978, 1173, "The Basicities of Substituted N-Trimethylammoniophenylacetamidates and N-Trimethylammoniocinnamamidates. The Hammett Correlations and the Thermodynamics of Protonation", by William H. Beck.
J.C.S. Perkin II, 1976, "The Basicities of N-Trimethylammonioacetamidate and of Substituted N-Trimethylammoniobenzamidates. The Hammett Correlation and the Thermodynamics of Protonation", by William H. Beck et al.
Tetrahedron Letters, No. 4, pp. 289-292, 1972, "The Curtius Rearrangeme
Casebier David
Furth Paul S.
Gallion Steve
Hogan, Jr. Joseph C.
Kaplan Alan
ArQule, Inc.
Burn Brian M.
LandOfFree
Hydroxyethyl aminimides does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Hydroxyethyl aminimides, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Hydroxyethyl aminimides will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-1372978