Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Reexamination Certificate
2005-11-28
2009-10-27
Wilson, James O (Department: 1624)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
Reexamination Certificate
active
07608623
ABSTRACT:
The present invention relates to novel compounds for inhibiting the urokinase plasminogen activator (uPA), which have high bioavailability and oral administerability, and also to the use thereof as therapeutic active compounds for the treatment of urokinase- or/and urokinase receptor-associated disorders such as, for example, tumors and metastasizing. The invention relates in particular to compounds containing hydroxyamidine or hydroxyguanidine groups.
REFERENCES:
patent: 7211670 (2007-05-01), Ag
patent: WO/03072559 (2003-09-01), None
Cecil Textbook of Medicine, 21th Edition (2001), Goldman & Bennett (Editors), W.B. Saunders Company (Publisher), Chapter 198, Principles of Cancer Therpay, pp. 1060-1074.
Http://www.healthline.com/galecontent/giant-cell-tumors. Accessed Aug. 2007.
Buergle Markus
Clement Bernd
Schmalix Wolfgang
Sperl Stefan
Wosikowski Katja
Murray Jeffrey H
Rothwell Figg Ernst & Manbeck P.C.
Wilex AG
Wilson James O
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