Hydroxyamidine and hydroxyguanidine compounds as urokinase...

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Reexamination Certificate

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Reexamination Certificate

active

07608623

ABSTRACT:
The present invention relates to novel compounds for inhibiting the urokinase plasminogen activator (uPA), which have high bioavailability and oral administerability, and also to the use thereof as therapeutic active compounds for the treatment of urokinase- or/and urokinase receptor-associated disorders such as, for example, tumors and metastasizing. The invention relates in particular to compounds containing hydroxyamidine or hydroxyguanidine groups.

REFERENCES:
patent: 7211670 (2007-05-01), Ag
patent: WO/03072559 (2003-09-01), None
Cecil Textbook of Medicine, 21th Edition (2001), Goldman & Bennett (Editors), W.B. Saunders Company (Publisher), Chapter 198, Principles of Cancer Therpay, pp. 1060-1074.
Http://www.healthline.com/galecontent/giant-cell-tumors. Accessed Aug. 2007.

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