Organic compounds -- part of the class 532-570 series – Organic compounds – Oxygen containing
Patent
1978-12-22
1981-08-18
Lone, Werren B.
Organic compounds -- part of the class 532-570 series
Organic compounds
Oxygen containing
568763, 568766, 424256, 424263, 26032647, 544172, 544358, 544360, 544399, 546186, 187546, 546190, 546194, 560163, 560164, 560173, C07C 3906, C07C 3910, C07C 4700
Patent
active
042848296
ABSTRACT:
Compounds useful for pharmacological and medicinal purposes having the formulae ##STR1## wherein R is H, C.sub.1 -C.sub.5 alkanoyl; R.sub.1 is H, benzyl, C.sub.1 14 C.sub.5 alkanoyl, P(O)(OH).sub.2, --CO(CH.sub.2).sub.2 COOH or a basic acyl group; each of R.sub.2 and R.sub.4 is H, C.sub.1 -C.sub.6 alkyl, phenyl, pyridyl or (CH.sub.2).sub.y C.sub.6 H.sub.5 ; y is 1-4; R.sub.3 is H or CH.sub.3 ; Z is C.sub.1 -C.sub.13 alkylene or --(alk.sub.1).sub.m --O--(alk.sub.2).sub.n --; each of (alk.sub.1) and (alk.sub.2) is C.sub.1 -C.sub.13 alkylene with the proviso that the summation of carbon atoms in (alk.sub.1) plus (alk.sub.2) is not greater than 13; each of m and n is 0 or 1; and W is H, pyridyl, phenyl, fluorophenyl or chlorophenyl; intermediates therefor and methods for their preparation and use.
REFERENCES:
patent: 3989741 (1976-11-01), Parker
patent: 4026952 (1977-05-01), Fischer et al.
patent: 4062978 (1977-12-01), Cole
Althuis Thomas H.
Harbert Charles A.
Johnson Michael R.
Melvin, Jr. Lawrence S.
Frost Albert E.
Knuth Charles J.
Lone Werren B.
Murphy Francis X.
Pfizer Inc.
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