Hydroxyalkane diphosphonic acids

Details Hydroxyalkane diphosphonic acids Hydroxyalkane diphosphonic acids

1978-09-21

1981-05-12

Daus, Donald G.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

2605025, 424200, 424211, C07D20712, C07F 902

Patent

active

042671086

ABSTRACT:
Hydroxyalkane diphosphonic acids having the formula ##STR1## wherein X is a member selected from the group consisting of ##STR2## and their water-soluble salts; as well as the process of preparing the same.
The compounds are excellent sequestering agents, especially for alkaline earth and earth metal ions. They are stabilizers for percompounds and are useful in the delaying of the setting times for gypsum. In addition, the compounds are useful in cosmetic preparations, such as toothpastes and mouthwashes where they prevent formation of tartar and plaque and are useful in therapy in the treatment of diseases related to the abnormal deposition or dissolution of difficultly soluble calcium salts in the animal body.

REFERENCES:
patent: 3925453 (1975-12-01), Clarke
patent: 3941772 (1976-03-01), Ploger et al.
Ploger et al., Z anorg. allg. Chem., 389, pp. 119-128, (1972).
Kabachnik et al., Chem. Abst, 69, 5682h, (1968).
Henkel C. A., 59, 11566 C & D (1963), Abstract of Belgian Patents 619,619 and 619,620, issued 3/7/71.

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