Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Recombinant or stably-transformed bacterium encoding one or...
Patent
1980-10-31
1982-01-12
Friedman, Stanley J.
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Recombinant or stably-transformed bacterium encoding one or...
424317, 560102, 562409, 562418, A61K 3119, A61K 31235, C07C 6976, C07C 5116
Patent
active
043105440
ABSTRACT:
The invention concerns novel 2-[4-(4-chlorophenyl)benzyloxy]acetic acids of the formula: ##STR1## in which R.sup.1 is hydrogen or (1-4C)alkyl, R.sup.2 is phenyl optionally bearing a halogeno substituent, and R.sup.3 is hydrogen or (1-4C)alkyl, and when R.sup.3 is hydrogen pharmaceutically acceptable base-addition salts thereof; and processes for their manufacture.
The compounds possess useful anti-arthritic properties coupled with desirable pharmacokinetic properties and the minimum of adverse properties, and the invention also concerns pharmaceutical compositions of such compounds for use in the treatment of arthritic joint diseases. A typical compound of the invention is 2-[4-(4-chlorophenyl)benzyloxy]-2-phenyl propionic acid.
Friedman Stanley J.
Imperial Chemical Industries Limited
LandOfFree
Hydroxyacetic acid derivatives with anti-arthritic properties does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Hydroxyacetic acid derivatives with anti-arthritic properties, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Hydroxyacetic acid derivatives with anti-arthritic properties will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-1541216