Hydroxy-substituted azetidinone compounds useful as hypocholeste

Details Hydroxy-substituted azetidinone compounds useful as hypocholeste Hydroxy-substituted azetidinone compounds useful as hypocholeste

1994-06-09

1997-05-20

Berch, Mark L.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

540361, 549273, 549295, C07D20508, A61K 31395

Patent

active

056313659

ABSTRACT:
A process for preparing compounds of the formula ##STR1## wherein R and R.sup.2 are independently --OH, --O(lower alkyl) or --0-benzyl and the remaining variables are as defined in the specification, comprising

REFERENCES:
patent: 4375475 (1983-03-01), Willard et al.
patent: 4983597 (1991-01-01), Yang et al.
patent: 5099034 (1992-03-01), Yoshida
patent: 5350868 (1994-09-01), Yoshida
Georg, Tet. Letters 26, 3903 (1985).
Hart, Tet. Letters 26, 5493 (1985).
Ram et al, Indian J. Chem., Sect B, 29B, 12 (1990), pp. 1134-1137.
Hoekman et al, J. Agric. Food Chem., 30 (1982), pp. 920-924.
Durst et al, Can. J. Chem., 50 (1972), pp. 3196-3201.
Otto et al, Liebigs Ann. Chem., (1983), pp. 1152-1161.
Panfil, et al, Heterocycles, 24, 6 (1986), pp. 1609-1617.
Schnitzer-Polokoff, et al, Comp. Biochem. Physiol., 99A (1991), pp. 665-670.
Witzum, Circulation, 80, 5 (1989), pp. 1101-1114.
Illingsworth, Drugs, 36(Supp. 3) (1988), pp. 63-71.
Allain, et al, Clin. Chem., 20, (1974), pp. 470-475.
Horie, et al, Atherosclerosis, 88 (1991), pp. 183-192.
Baxter, er al, J. Biological Chem., 267, 17 (1992), pp. 11705-11708.
Current Drugs: Anti-Atherosclerotic Agents--Summary Factfile, May, 1992.
Harwood, et al, Journal of Lipid Research, 34 (1993), pp. 377-395.
Salisbury Atherosclerosis, 115 (1995), pp. 45-63.
Burrier Biochemical Pharmacology, 47, 9 (1994), pp. 1545-1551.

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