Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Patent
1996-06-17
1997-12-16
Grumbling, Matthew V.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
544366, A61K 31495, C07D40300
Patent
active
056985576
ABSTRACT:
A compound represented by the formula I ##STR1## wherein X is independently both F or both Cl or one X is independently F and the other is independently Cl; R.sub.1 is a straight or branched chain (C.sub.3 to C.sub.8) alkyl group substituted by one or two hydroxy moieties, an ether or ester thereof (e.g., a polyether ester, heterocyclic ester amino acid ester or phosphate ester) thereof and the carbon with the asterisk (*) has the R or S absolute configuration or a pharmaceutically acceptable salt thereof and pharmaceutical compositions thereof useful for treating and/or preventing fungal infections are disclosed.
REFERENCES:
patent: 4791111 (1988-12-01), Heeres et al.
patent: 5023258 (1991-06-01), Gymer et al.
patent: 5039676 (1991-08-01), Saksena et al.
Girijavallabhan Viyyoor M.
Lovey Raymond G.
Pike Russell E.
Saksena Anil K.
Coleman Brenda
Grumbling Matthew V.
Hoffman Thomas D.
Schering Corporation
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