Hydroxy phenylbutazone derivatives and their preparation

Details Hydroxy phenylbutazone derivatives and their preparation Hydroxy phenylbutazone derivatives and their preparation

1975-07-28

1976-07-06

Moyer, Donald B.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Parasitic organism or component thereof or substance...

260310B, A61K 31415, C07D23134, C07D23136

Patent

active

039682196

ABSTRACT:
Bis-hydroxyphenylbutazone esters of alkanedioic acids of the formula ##SPC1##
Wherein n is an integer from 1 to 18, inclusive; R.sub.1 is hydrocarbon of 3-9 carbon atoms, optionally substituted by oxo or interrupted by thia, sulfinyl, or sulfonyl; and R.sub.2 is a hydrogen atom, a fluorine atom, a chlorine atom, lower alkyl of 1-4 carbon atoms, or trifluoromethyl, preferably in the ortho or para position, possess topical anti-inflammatory activity.

REFERENCES:
patent: 3457273 (1969-07-01), Rumpf et al.

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