Chemistry of carbon compounds – Miscellaneous organic carbon compounds – C-metal
Patent
1978-06-26
1979-04-17
Trousof, Natalie
Chemistry of carbon compounds
Miscellaneous organic carbon compounds
C-metal
C07D20982
Patent
active
041500318
ABSTRACT:
A process for the preparation of 6-chloro-.alpha.-methylcarbazole-2-acetic acid from 6-chloro-.alpha.-hydroxy-.alpha.-methylcarbazole-2-acetic acid and/or 6-chloro-.alpha.-methylene-2-carboxylic acid, is described. The preparation of intermediates, such as, 6-chloro-.alpha.-hydroxy-.alpha.-methylcarbazole-2-acetic acid and lower alkyl carbazole-2-oxalate, inter alia, is also described.
REFERENCES:
patent: 3896145 (1975-07-01), Berger et al.
patent: 4057640 (1977-11-01), Biere et al.
Gore "Friedel-Crafts and Related Reactions", vol. III, pt. 1, pp. 94-95 (1964).
Sumpter et al., "The Chemistry of Heterocyclic Compounds", vol. 8, pp. 70-109 (1954).
Clemence et al., "J. Med. Chem.", vol. 9, p. 390 (1974).
Berger Leo
Corraz Alfred J.
Parrish David R.
Scott John W.
Gould George M.
Hoffmann-La Roche Inc.
Isgro William G.
Ramsuer R. W.
Saxe Jon S.
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