Hydroxy furanone preparation

Details Hydroxy furanone preparation Hydroxy furanone preparation

1990-05-18

1992-09-22

Ivy, C. Warren

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C07D30758

Patent

active

051498405

ABSTRACT:
The invention provides a process for the preparation of natural 5-methyl- and 2,5-dimethyl-4-hydroxy-2,3-dihydrofuran-3-one, by heating and reacting a pentose or 6-deoxyhexose in the presence of an amino acid and directly separating, the hydroxyfuranone from the reaction mixture by distillation under reduced pressure. Preferably the distillation is carried out in the presence of a high boiling organic solvent, particularly propylene glycol and glycerol. The amino acid is preferably lysine, proline or hydroxyproline.

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