Hydroxy and ether containing phenothiazine derivatives

Details Hydroxy and ether containing phenothiazine derivatives Hydroxy and ether containing phenothiazine derivatives

1975-01-21

1976-06-01

Jiles, Henry R.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Bacterium or component thereof or substance produced by said...

260243A, A61K 2700, C07D27928

Patent

active

039610551

ABSTRACT:
Phenothiazine derivatives of the formula: ##SPC1##
Wherein X represents methylthio, methylsulphonyl or dimethylsulphamoyl, R represents hydrogen, alkyl of 1 through 10 carbon atoms, phenylalkyl containing 1 through 4 carbon atoms in the alkyl part, or tetrahydropyranyl, A represents --(CH.sub.2).sub.3 -- or --CH.sub.2 --CH(CH.sub.3)--CH.sub.2 --, and R.sub.1 represents hydrogen, alkanoyl containing 1 through 16 carbon atoms in the alkyl part or alkenoyl containing 2 through 16 carbon atoms in the alkenyl part, are new compounds possessing pharmacodynamic properties; they are particularly active as anti-emetic agents.

REFERENCES:
patent: 3150129 (1964-09-01), Jacob et al.
patent: 3879551 (1975-04-01), Blondel et al.

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