Organic compounds -- part of the class 532-570 series – Organic compounds – Carboxylic acid esters
Patent
1982-06-07
1984-06-12
Helfin, Bernard
Organic compounds -- part of the class 532-570 series
Organic compounds
Carboxylic acid esters
560170, 562568, C07C10130
Patent
active
044543328
ABSTRACT:
Disclosed is a process for the stereocontrolled total synthesis of thienamycin from acetone dicarboxylate via intermediate II: ##STR1## wherein R is a readily removable carboxyl protecting group.
REFERENCES:
patent: 4282148 (1981-08-01), Liu et al.
patent: 4287123 (1981-09-01), Liu et al.
Liu Thomas M. H.
Melillo David G.
Ryan Kenneth M.
Shinkai Ichiro
Sletzinger Meyer
Helfin Bernard
Merck & Co. , Inc.
Szura Daniel T.
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