Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1986-07-23
1987-06-16
Jiles, Henry R.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514337, 514469, 546256, 546269, 549463, A61K 3134, A61K 31557, C07D30700
Patent
active
046736859
ABSTRACT:
Hydroximic acids of 7-oxabicycloheptane substituted ether and thioether prostaglandin analogs are provided having the structural formula ##STR1## wherein Y is O or ##STR2## and including all stereoisomers thereof. The compounds are inhibitors of prostaglandin and biosynthesis and as such are useful, for example, as anti-allergy and antiinflammatory agents and also as antipsoriatic agents.
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Gordon Eric M.
Simpkins Ligaya M.
Varma Ravi K.
Dentz Bernard I.
E. R. Squibb & Sons Inc.
Jiles Henry R.
Levinson Lawrence S.
Rodney Burton
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