Organic compounds -- part of the class 532-570 series – Organic compounds – Unsubstituted hydrocarbyl chain between the ring and the -c-...
Patent
1989-10-26
1990-12-25
Bond, Robert T.
Organic compounds -- part of the class 532-570 series
Organic compounds
Unsubstituted hydrocarbyl chain between the ring and the -c-...
C07D49816
Patent
active
049804669
ABSTRACT:
A process is described involving an alkaline rearrangement of FK-506 producing a new decarbonylated 22-membered macrocycle rearrangement derivative of FK-506, i.e. C.9, nor-keto FK-506.
REFERENCES:
patent: 4894366 (1980-01-01), Okuhara et al.
Askin David
Jones Todd K.
Reamer Robert A.
Shinkai Ichiro
Volante Ralph P.
Bond Robert T.
Merck & Co. , Inc.
North Robert J.
Pfeiffer Hesna J.
Winokur Melvin
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