Chemistry of inorganic compounds – Phosphorus or compound thereof – Oxygen containing
Reexamination Certificate
2005-05-06
2008-12-23
Langel, Wayne (Department: 1793)
Chemistry of inorganic compounds
Phosphorus or compound thereof
Oxygen containing
C424S489000
Reexamination Certificate
active
07468172
ABSTRACT:
The present invention is directed to calcium phosphates in granular form having an X-ray diffraction pattern characteristic of hydroxyapatite in which a portion of the anions of the crystal lattice are substituted with carbonate anions and which have good compressibility and flow properties in direct compression applications.The invention is also directed to the methods for preparing the calcium phosphate aforesaid granules characterized in that the methods include the processing of a brushite dicalcium phosphate solution having a specified particle size distribution using a solution of an alkaline earth carbonate for a sufficient period of time to allow the transformation of the brushite calcium phosphate into hydroxyapatite calcium phosphate.
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Godber John
Leite Lorraine
Innophos, ,Inc.
Langel Wayne
McCarter & English LLP
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