Hydroxamic acids and acyl hydroxamines as naaladase inhibitors

Details Hydroxamic acids and acyl hydroxamines as naaladase inhibitors Hydroxamic acids and acyl hydroxamines as naaladase inhibitors

2005-04-26

2005-04-26

Richter, Johann (Department: 1621)

Organic compounds -- part of the class 532-570 series

Organic compounds

Carboxylic acids and salts thereof

C562S405000, C562S426000, C562S427000, C562S429000, C562S430000, C562S433000, C562S434000, C562S435000, C562S471000, C514S568000, C514S572000, C514S625000

Reexamination Certificate

active

06884907

ABSTRACT:
This invention relates to new compounds, pharmaceutical compositions and diagnostic kits comprising such compounds, and methods of using such compounds for inhibiting NAALADase enzyme activity, detecting diseases where NAALADase levels are altered, effecting neuronal activity, effecting TGF-β activity, inhibiting angiogenesis, and treating glutamate abnormalities, neuropathy, pain, compulsive disorders, prostate diseases, cancers and glaucoma.

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