Hydroxamic acid derivatives

Details Hydroxamic acid derivatives Hydroxamic acid derivatives

1997-04-04

1999-10-05

Rotman, Alan L.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Ester doai

514531, 514532, 514533, 514534, 558411, 558418, 558421, 562433, 562443, A61K 31215, C07C22948, C07C25502

Patent

active

059625210

ABSTRACT:
The present invention relates to hydroxamic acid derivatives that inhibit N-Acetylated .alpha.-Linked Acidic Dipeptidase (NAALADase) enzyme activity, pharmaceutical compositions comprising such derivatives, and methods of using such derivatives to inhibit NAALADase activity, to treat a glutamate abnormality and to treat a prostate disease in an animal.

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