Hydroxamic acid derivative

Details Hydroxamic acid derivative Hydroxamic acid derivative

1995-03-24

1995-12-05

Dees, Jose G.

Organic compounds -- part of the class 532-570 series

Organic compounds

Thiocarboxylic acids or salts thereof

562431, 562426, 562448, C07C25904

Patent

active

054731003

ABSTRACT:
##STR1## A compound represented by general formula (I), a pharmaceutical composition containing same, a process for the production thereof, and an intermediate therefor. In formula (I) R.sup.1 represents lower alkyl which may be substituted by a substituent selected from the group consisting of mercapto, lower alkylthio, arylthio and lower acylthio; R.sup.2, R.sup.3 and R.sup.4 may be the same or different from one another and each represents lower alkyl; X represents oxygen or sulfur; and Y represents a single bond or lower alkylene. The compound (I) has a matrix metalloprotease inhibitory activity and is useful for preventing and treating diseases caused by the progress of connective tissue breakage.

REFERENCES:
patent: 4599361 (1986-07-01), Dickens et al.

Affiliated with

Also associated with

Rating

Hydroxamic acid derivative does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Hydroxamic acid derivative, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Hydroxamic acid derivative will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1375251