Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Patent
1994-04-18
1996-05-07
Gerstl, Robert
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
514317, 514357, 514394, 514400, 514427, 514428, 514616, 544168, 5483097, 5483381, 548561, 548571, 564153, 546233, 546337, C07C25906, A61K 3113
Patent
active
055146775
ABSTRACT:
Compounds of general formula I: ##STR1## wherein: A represents the group --NH.sub.2, a substituted acyclic amine or a heterocyclic base;
have collagenase inhibition activity and are useful in the management of disease involving tissue degradation and/or the promotion of wound healing. Diseases involving tissue degradation include arthropathy (particularly rheumatoid arthritis), inflammation, dermatological diseases, bone resorption diseases and tumour invasion.
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patent: 5304604 (1984-04-01), Davidson
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Amomoto et al, Microbiol. Immunol. 28 85 (1984) Abstact Only.
Crimmin Michael J.
Davidson Alan H.
Dickens Jonathan P.
British Biotech Pharmaceuticals Limited
Gerstl Robert
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