Hydroxamic acid and pharmaceutical preparations containing the s

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Radical -xh acid – or anhydride – acid halide or salt thereof...

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2605005H, C07C 8310, A61K 31185, A61K 31045, A61K 31075

Patent

active

046704698

ABSTRACT:
Hydroxamic acids, pharmaceutical preparations containing the same, new .omega.(2'-naphthoxy)-alkylhydroxamic acids as well as a process for their production are disclosed. The new compounds display antiasthmatic and further pharmacologically valuable characteristics. They are prepared by reacting the corresponding carboxylic acid ester or amide with hydroxylamine or its salt under the described conditions into compounds of Formula I,

REFERENCES:
patent: 2279560 (1942-04-01), Dietrich
patent: 2279973 (1942-04-01), Dietrich
Buraczewski et al., Przemysl Chemiczny, vol. 43, No. 11, (1964), pp. 626-629.
Wise et al., J. Am. Chem. Soc., vol. 77, (1955), pp. 1058, 1059.
Epstein et al., Proc. Soc. Exptl. Biol., vol. 92, (1956), pp. 660-662.

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