Hydroxamic acid and carboxylic acid derivatives, process for the

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Radical -xh acid – or anhydride – acid halide or salt thereof...

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562621, A61K 3119, C07C23900

Patent

active

056188447

ABSTRACT:
This disclosure relates to a novel class of hydroxamic and carboxylic acid based matrix metalloproteinase inhibitor derivatives. The disclosure further relates to pharmaceutical compositions containing such compounds and to the use of such compounds and compositions in the treatment of matrix metalloproteinase induced diseases.

REFERENCES:
Blodgett, et al., J. Am. Chem. Soc. 107(14), 4305-13.

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