Hydroxamate inhibitors of interleukin-1.beta. converting enzyme

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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514412, 514416, 514417, 514418, 514424, 514425, 546 18, 546122, 546139, 546249, 548472, 548475, 548486, 548512, 548514, 548530, 5483001, 548146, 560312, 562444, 544242, 549 29, 549 49, 549434, A61K 31405, A61K 3144, C07C25908, C07C22932, C07D20934, C07D20946, C07D20948, C07D22120

Patent

active

059197900

ABSTRACT:
The present invention relates to compounds that are inhibitors of interleukin-1.beta. converting enzyme that have the Formula II ##STR1## This invention also relates to a method of treatment of stroke, inflammatory diseases, septic shock, reperfusion injury, Alzheimer's disease, shigellosis, and to a pharmaceutically acceptable composition that contains a compound that is an inhibitor of interleukin-1.beta. converting enzyme.

REFERENCES:
patent: 5656627 (1997-08-01), Bemis et al.

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