Hydrosoluble extracts of mycobacteria

Details Hydrosoluble extracts of mycobacteria Hydrosoluble extracts of mycobacteria

1975-09-04

1977-01-04

Rosen, Sam

Drug, bio-affecting and body treating compositions

Whole live micro-organism, cell, or virus containing

Genetically modified micro-organism, cell, or virus

A61K 3900, A61K 3902

Patent

active

040013952

ABSTRACT:
Hydrosoluble extracts of mycobacteria suitable as immunological adjuvants are prepared. These extracts have a molecular weight between 3,500 and 30,000 and adjuvant, non-arthrogenic properties. The delipidated bacterial residues of mycobacteria are subjected to a mild extraction, then the so-obtained substance is isolated and purified by physicochemical methods, or the delipidated bacterial residues of mycobacteria are treated by means of pyridine optionally in the presence of acetic anhydride, then the obtained products are treated with ethanol or water, and the hydrosoluble substances are isolated and purified by physicochemical methods.

REFERENCES:
chem. Abst. 8th Collective Index, vol. 66-75 (1967-1971) p. 19857s.

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