Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Ether doai
Patent
1995-12-13
1999-03-09
Stockton, Laura L.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Ether doai
568650, 568651, C07C 43205, A61K 31085
Patent
active
RE0361399
ABSTRACT:
Novel hydroquinone derivatives of the formulae (I) and (II), ##STR1## wherein R.sup.1 is an alkyl group having 7 to 11 carbon atoms, ##STR2## wherein each of R.sup.2 to R.sup.5 is independently a hydrogen atom, a lower alkyl group or a lower alkoxy group provided that at least one of R.sup.2 to R.sup.5 is a lower alkyl group or a lower alkoxy group, and R.sup.6 is an alkyl group having a carbon chain of at least 2 carbon atoms. as compounds having antioxidant activity and tumor incidence inhibiting activity, and an antioxidant and a tumor incidence inhibitor containing, as an active ingredient, a hydroquinone derivative of the formula (III), ##STR3## wherein each of R.sup.7 to R.sup.10 is independently a hydrogen atom, a lower alkyl group or a lower alkoxy group, and R.sup.11 is an alkyl group having a carbon chain of at least 2 carton atoms, and/or a salt thereof.
REFERENCES:
patent: 2459540 (1949-10-01), Rosenwald
patent: 4933504 (1990-06-01), Correale et al.
patent: 5059627 (1991-10-01), Goto et al.
patent: 5387718 (1995-02-01), Kohler et al.
John et al., Chem. Ber., 73(1940), 995-1001, 1940.
Matsumoto Hitoshi
Niiro Yasunori
Satoh Toshio
Nippon Hypox Laboratories Incorporated
Stockton Laura L.
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