Catalyst – solid sorbent – or support therefor: product or process – Catalyst or precursor therefor – Silicon containing or process of making
Patent
1996-10-25
1999-03-23
Achutamurthy, Ponnathapura
Catalyst, solid sorbent, or support therefor: product or process
Catalyst or precursor therefor
Silicon containing or process of making
502407, 436 71, 436 72, 554175, 554193, B01J 2108, B01J 2010
Patent
active
058859217
ABSTRACT:
There is provided a process for the preparation of a highly reactive hydrophobic silica capable of lipophilic binding of lipids present in aqueous media, in particular body fluids. The hydrocarbon substituted silica utilized in the first step of this process may be prepared from hydrophilic silica, suitably pyrogenic silica. This is then treated with a volatile hydrocarbon substituted silicon compound. The next step of the process comprises treating the substituted hydrophobic silica with an alcohol. In order to enable the thus produced material to selectively adsorb lipids in the presence of protein, to the substantial non absorption of the proteins (other than lipoproteins), a further step is carried out. This comprises treating with aqueous ammonia or amines wherein substituents on the amine nitrogen may be the same or different. Also included in the scope of the present invention is the use of the above materials in procedures for absorbing lipids from aqueous media, suitably body fluids both together with and to he substantial exclusion of proteins.
REFERENCES:
patent: 5171870 (1992-12-01), Kulpraghipanja
patent: 5304243 (1994-04-01), Yamaguchi et al.
Achutamurthy Ponnathapura
Behr Esq. Omri M.
LigoChem, Inc.
Ponnaluri P.
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