Hydrophobic nucleic acid probes

Details Hydrophobic nucleic acid probes Hydrophobic nucleic acid probes

1995-02-06

1996-09-03

Jones, W. Gary

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving nucleic acid

514 44, 536 221, 536 2532, 935 77, 935 78, C07H 2102, C07H 2104, C12Q 168

Patent

active

055522807

ABSTRACT:
A polynucleotide which has been modified by a hydrophobic moiety so that the polynucleotide attaches to a substrate by the hydrophobic moiety, rather than by a portion of the polynucleotide, thereby allowing the polynucleotide to be available for hybridization.

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patent: 4716103 (1987-12-01), Hunger et al.
patent: 4806546 (1989-02-01), Carrico et al.
patent: 4868105 (1989-09-01), Urdea et al.
patent: 4925921 (1990-05-01), Avrameas et al.
Rubin et al., J. Immunol. Methods (1983) 63:359-366.

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