Hydrophobic nucleic acid probe

Details Hydrophobic nucleic acid probe Hydrophobic nucleic acid probe

1995-05-15

1997-12-30

Jones, W. Gary

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving nucleic acid

536 221, 536 243, 536 2532, 514 44, C12Q 168, C07H 2102, C07H 2104

Patent

active

057028931

ABSTRACT:
A method for binding a target polynucleotide in a sample is provided. The method uses an assay reagent which is a substrate noncovalently bound to a hydrophobic moiety which is part of a polynucleotide capture probe. This assay reagent is contacted with the sample under conditions which permit hybridization between said capture probe and said target polynucleotide, thereby binding the target polynucleotide.

REFERENCES:
patent: 4379843 (1983-04-01), Cashion et al.
patent: 4588682 (1986-05-01), Groet et al.
patent: 4777120 (1988-10-01), Dattagupta et al.
patent: 5217492 (1993-06-01), Guire et al.
patent: 5354657 (1994-10-01), Holtke et al.
Matthews et al., Analytical Biochem. 169: 1-25, 1988.
Wolf et al., Nuc. Acids Res. 15(7): 2911-2926, 1987.
Kremsky et al., Nuc. Acids Res. 15(7): 2891-2909, 1987.

Affiliated with

Also associated with

Rating

Hydrophobic nucleic acid probe does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Hydrophobic nucleic acid probe, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Hydrophobic nucleic acid probe will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-201259