Hydrophobic moment of multi-domain proteins

Details Hydrophobic moment of multi-domain proteins Hydrophobic moment of multi-domain proteins

2011-08-30

2011-08-30

Dejong, Eric S (Department: 1631)

Data processing: structural design, modeling, simulation, and em

Simulating nonelectrical device or system

Biological or biochemical

C702S019000

Reexamination Certificate

active

08010332

ABSTRACT:
Techniques for protein structure analysis are provided. In one aspect, an apparatus for characterizing a multi-domain protein structure comprises the following steps. For at least one domain, a hydrophobic dipole, e.g., defined as a first-order hydrophobic moment of the domain, is calculated. A score representing the orientation of the hydrophobic dipole of the at least one domain relative to a hydrophobic dipole of one or more other domains of the multi-domain protein structure is then calculated.

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