Hydrophilic renin inhibitors, their preparation and use

Details Hydrophilic renin inhibitors, their preparation and use Hydrophilic renin inhibitors, their preparation and use

1988-09-14

1991-09-03

Bond, Robert T.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Silicon containing doai

514332, 514356, 546 14, 546255, 546318, 546322, A61K 31695, A61K 31455, C07D21366, C07F 710

Patent

active

050455370

ABSTRACT:
Hydrophilic renin inhibitors, especially of formula ##STR1## wherein R.sub.1, W, o, m, n, A, B, C and D possess the definitions given in claim 2, processes for their production and their use in the treatment of hypertension, cardiac insufficiency and the treatment of diseases caused by retroviruses.

REFERENCES:
Cumin et al., "Biochem., Biophys. Acta", vol. 913, pp. 10-19, (1987).

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