Hydrophilic packing material for chromatography

Stock material or miscellaneous articles – Coated or structually defined flake – particle – cell – strand,... – Particulate matter

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521 53, 521 55, 521905, 525 58, 210635, 2101982, B32B 300, C08F22600

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active

043395007

ABSTRACT:
Grains of a totally porous, hydroxyl group-containing, nonionic and hydrophilic synthetic cross-linked polymer having alcoholic hydroxyl and ether groups as main hydrophilic groups and having as a main skeleton a chemical structure including carbon atoms, hydrogen atoms and oxygen atoms bonded through single bonds, said synthetic polymer having a hydroxyl group density of 1 to 15 milliequivalents/g, a specific surface area of 5 to 1000 m.sup.2 /g and a water regain of 0.3 to 3.0 g/g. Such grains have been found to be a packing material or gel for high speed, aqueous gel permeation chromatography. The packing material of the present invention which comprises grains of a hydroxyl group-containing nonionic and hydrophilic synthetic cross-linked polymer has a chemical structure obtained by reacting a totally porous, hydroxyl group-containing, nonionic polymer with a polyfunctional substance capable of reacting with the hydroxyl groups of said polymer while forming cross-linking ether groups.

REFERENCES:
patent: 3002823 (1961-10-01), Flodin et al.
patent: 3208994 (1965-09-01), Flodin
patent: 3369007 (1968-02-01), Flodin
patent: 3586626 (1971-06-01), Heitz et al.
patent: 3598245 (1969-10-01), Determann et al.
patent: 4105598 (1978-08-01), Yen et al.

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