Hydrophilic laminate useful for making dispensing device

Details Hydrophilic laminate useful for making dispensing device Hydrophilic laminate useful for making dispensing device

1977-10-25

1980-09-16

Bell, James J.

Stock material or miscellaneous articles

Structurally defined web or sheet

Including components having same physical characteristic in...

128260, 428280, 428284, 428287, 428913, B32B 700

Patent

active

042230616

ABSTRACT:
A self-powered device for dispensing a medicament is disclosed. The device comprises (1) a rigid housing defining an internal space, (2) a container in the housing formed of a stretched polymer and having a passage-way connecting the container with the exterior of the device, (3) a medicament in the container, and (4) and expandable laminate surrounding the container positioned between the interior of the housing and the exterior of the container. The laminate comprises (a) a lamina of an absorbent material laminated to (b) a lamina of a swellable, hydrophilic polymer. In operation, when the device is in a biological fluid environment, fluid therefrom is imbibed by the laminate into the housing, causing the laminate to expand and exert pressure on the container, thereby shrinking the container to an unstretched state, which decreases its volume and concomitantly pumps medicament through the passageway at a controlled rate over time.

REFERENCES:
patent: 2546705 (1951-03-01), Strawinski
patent: 3123075 (1964-03-01), Stamberger
patent: 3480016 (1969-11-01), Costanza et al.
patent: 3760984 (1973-09-01), Theeuwes
patent: 3926891 (1975-12-01), Gross et al.
patent: 3971376 (1976-07-01), Wichterle
patent: 3987790 (1976-10-01), Eckenhoff et al.
patent: 3992562 (1976-11-01), Denzinger et al.
patent: 3995631 (1976-12-01), Higuchi et al.

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