Hydronaphthalene carboxylic acids and derivatives

Chemistry of carbon compounds – Miscellaneous organic carbon compounds – C-metal

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260465R, 260465D, 260465G, 260471R, 260473F, 260475SC, 260515R, 260515A, 260515P, 260518R, 260520D, 260544R, 260558R, 260558A, 424308, 424309, 424317, 424319, 424324, C07C 6995

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039681424

ABSTRACT:
Compounds of the formula ##EQU1## in which Ph represents an ortho-phenylene radical which contains in position 4 or 5 an unsubstituted or substituted hydrocarbon radical of aliphatic character, R represents a lower alkyl radical or especially a hydrogen atom, Z represents a free, esterified or amidated carboxyl group, A represents an ethylene radical and X stands for two hydrogen atoms or especially for an oxo group, are useful as chemotherapeutic and prophylactic agents against pain and inflammation.

REFERENCES:
patent: 3502697 (1970-03-01), Woodward
patent: 3565904 (1971-02-01), Juby et al.
Fujita et al., Agr. Biol. Chem., vol. 25, No. 9, pp. 710-718 (1961).
Chemical Abs. CIBA Ltd. vol. 68, col. 59449-59450.
Chemical Abs. Battelle Inst. vol. 63, col. 8327-8329.

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