Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Particulate form
Patent
1996-04-17
1999-01-12
Page, Thurman K.
Drug, bio-affecting and body treating compositions
Preparations characterized by special physical form
Particulate form
424475, 424470, 424494, 424480, A61K 914
Patent
active
058584099
ABSTRACT:
The present invention provides a method for preparing a spray-dried compressible granular formulation for preparing pharmaceutical tablets in which hydrolyzed cellulose is used as a granulation aid, the resulting granulations, and pharmaceutical tablets compressed from such granules. In these formulations there is employed from 1 to 97% by weight pharmaceutical active, from about 3 to 99% by weight hydrolyzed cellulose, based on the dry weight of the granulation, and optionally conventional granulation and/or tableting additives such as surfactants, disintegrants and antiadherents/flow aids.
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Erkoboni David F.
Karetny Marc S.
Stamato Howard J.
Vladyka, Jr. Ronald S.
Andersen Robert L.
Benston, Jr. William E.
Cupoli Anthony L.
FMC Corporation
Page Thurman K.
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